TESTOSTERONE ; CAS 58-22-0; Androgen and anabolic hormone drugs
||Virilon; Androst-4-en-17b-ol-3-one; 17b-Hydroxyandrost-4-ene-3-one
|CAS Registry Number
||45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble18.2 mg/ml
Testosterone is an androgen secreted by interstitial cells of testis, and it is also the most active androgen, which can promote the normal development of male organs and side sex characteristics of human and animal, sperm maturation, and promote protein synthesis metabolism of the body, and make muscle development. Testosterone is also the major natural androgen in mammals. It is a steroid hormone with 19 carbon atoms. It is the main androgen secreted by the testes, and the adrenal cortex secretes very little testosterone. Testosterone is important for the development of male accessory sex organs and secondary sexual characteristics. In the blood, testosterone binds either nonspecifically to plasma albumin or to plasma testosterone-estradiol binding globulin. In peripheral tissues, testosterone can be converted to estradiol and estrone. The liver is the main organ for testosterone degradation and metabolism, in which the A ring of testosterone is reduced and converted to 17-ketone steroids by the action of 17-β -hydroxysteroid dehydrogenase, including androsterone, isoandrosterone and procholanolone, which are excreted in urine by combining with glucuronic acid or sulfate. Most of the major metabolites in urine are excreted in the form of glucuronic acid, a member of the 17-keto steroid.
It is used for the replacement treatment of no testosterone, male menopause syndrome, impotence and other diseases.
Zhejiang chemical import and export co., LTD. (zhejiang), formerly known as zhejiang branch of China national chemical import and export corporation, was established in December 1980. In 1988, he was transferred from Sinochem Corporation to be in charge of Zhejiang Provincial Department of Commerce and was renamed Zhejiang Chemical Import and Export Company. In 2003, the company changed its name to Zhejiang Chemical Import and Export Co., Ltd after the reform of state-owned enterprise shareholding system.
In 2008, it was incorporated into Zhejiang International Trade Group (one of the top 500 enterprises in China) and became the core member of the group's business circulation sector. The registered capital of the company is 72.5 million yuan, of which 38% are owned by the state and 62% are owned by employees.
There are 195 employees in the company, more than 79% of whom have bachelor's degree, 36% of whom are graduate students, and more than 90% of the salesmen have pharmaceutical and chemical background. The company is mainly engaged in the import and export trade of pharmaceutical raw materials and intermediates, dyes, pesticides, basic chemicals, fine chemicals, food and feed additives, pharmaceutical preparations and other products. The company has established close economic and trade relations with more than 100 countries and regions around the world. The company has wholly-owned subsidiaries Ruike International Trade Co., Ltd., Zhejiang Ruikai Chemical Co., Ltd., Zhejiang Fukai Import and Export Co., Ltd., joint-stock enterprise Zhejiang Aotokang Pharmaceutical Group Co., Ltd.
In recent years, especially since the establishment of the new team in 2019, the company has adhered to the development led by the party building, energized by reform, and improved efficiency by management. The company has shown a steady upward momentum of development. In 2020, the company achieved revenue of 3.337 billion yuan, total profit of 56.12 million yuan, total import and export of 450 million dollars.
In 2019, the company was rated as China Council for the Promotion of International Trade (CCPIT) Recommended Certification Enterprise, Top 100 International Pharmaceutical Enterprises -- a high-quality supplier and partner in the international market; In 2020, Zhejiang Provincial Department of Commerce and other units rated as the province's epidemic prevention and medical materials import outstanding contribution enterprise, Zhejiang Provincial Tax Bureau identified as the export tax rebate enterprises.