|Cas No:||101831-37-2||Ec No:||1806241-23-5|
|Molecular Formula:||C17H9Cl3N4O2||Molecular Weight:||407.64|
CAS no 101831-37-2,
Aktteva Biopharma LLP
|CAS Registry Number||101831-37-2|
Decazulil is a triazine phenylacetonitrile compound, a novel, high efficiency (only 1g of this compound is added per ton of feed), low toxicity (excessive 50 times no poisoning phenomenon was found) Chemicalbook anti-coccidiosis, widely used in chicken coccidiosis. In addition to a variety of coccidiosis prevention and treatment, can also be used to prevent duck, quail, Turkey, goose and rabbit coccidiosis.
Analogous to streptomycin, spectinomycin binds with ribosomal 30 S subunits of microorganisms and inhibits protein synthesis; however, incorrect reading of the genetic code does not take place. Despite the broad spectrum of activity, spectinomycin is used only for gonococci infections. Other Gram-negative bacteria begin to display resistance during treatment. It is effective with respect to most strains of gonococci, as well as a number of other Gram-negative microorganisms.
It is used for treating severe gonorrheal urethritis and proctitis in men, and severe gonorrheal proctitis in women, which is caused by strains of gonococci that are sensitive to the drug. Synonyms of this drug are actinospectocin, spectam, togamicin, and others.
Spectinomycin finds principal application in the treatment of gonorrhea. It should be noted that the antibiotic resistance among N. gonorrhoeae has caused a number of therapeutic problems. It has been found that only by escalating the antibiotic doses and using probenecid to retard the excretion of penicillin and ampicillin (the drugs of choice) has the continued effective use of penicillin, ampicillin, and tetracycline been possible. Even with modifications in the therapy, from 3 to 8% of cases fail to respond to the usual regimens for uncomplicated gonorrhea. Thus, the treatment of uncomplicated gonorrhea that fails to respond to the usual regimen is spectinomycin therapy.
Spectinomycin is an aminocyclitol antibiotic. It is used as a medicine in humans to treat Neisseria gonorrhoeae and is also used in veterinary medicine, especially in poultry, pigs and cattle. Cases of dermatitis have been reported in veterinary practice.