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Veterinary Powder Medicine Raw Materials Altrenogest Animal Pill CAS 850-52-2

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Veterinary Powder Medicine Raw Materials Altrenogest Animal Pill CAS 850-52-2

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Product Details:

Place of Origin: China
Brand Name: PooChun
Certification: ISO9001 SGS HACCP
Model Number: 850-52-2

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Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1~10 kg / Al-Pt bag,10kg / 25kg fiber drum
Delivery Time: 1-3days after payment
Payment Terms: T/T, L/C
Supply Ability: 500 ton per Month
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Detailed Product Description
CAS: 850-52-2 Type: Estrogen Hormone Steroids
Use: Animal Pill MF: C21H26O2
Appearance: Powder Payment Terms: T/T, Western Union, Paypal, Moneygram
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For Veterinary Medicine Pharmaceutical Raw Materials Altrenogest Animal pill 850-52-2





Altrenogest ( or allyltrenbolone ) is a synthetic trienic C21 steroidal progestomimetic, belonging to the 19-nor - testosterone series. It is an orally active ( pro ) gestagen. Like all steroids, altrenogest acts by its liposolubility by penetrating the target cells where it binds to specific receptors.


Progestins are primarily produced endogenously by the corpus luteum. They transform proliferative endometrium to secretory endometrium, enhance myometrium hypertrophy and inhibit spontaneous uterine contraction. Progestins have a dose - dependent inhibitory effect on the secretion of pituitary gonadotropins and also have some degree of estrogenic, anabolic and androgenic activity.






1. In vitro research


An in vitro yeast structure - activity relationships bioassay study found that altrenogest was the most potent agonist of both the progesterone receptor ( PR ) and the androgen receptor ( AR ) of a large selection of other progestogens as well as anabolic - androgenic steroids ( AAS ). The observed potency of altrenogest even exceeded that of metribolone ( methyltrienolone, R -1881 ), which was the second most potent compound. In the study, it showed an EC50 of 0.64 nM for the AR and 688% of the relative activational potency of testosterone and an EC50 of 0.3 nM and 1,300% of the relative activational potency of progesterone, with an AR/PR activational potency ratio of 0.53.

Although very potent in both activities in vitro, the AR / PR activational potency ratio of altrenogest was in the same range as that of other 19- nortestosterone progestins such as norethisterone, noretynodrel, norgestrel, and allylestrenol ( ratio for all < 1.0 ), whereas the AR/PR activational potency ratio of its 17α - deallylated AAS analogue trenbolone was, at 64, profoundly increased ( although the ratio of metribolone ( the 17α - methylated variant of altrenogest ), at 0.56, was almost the same as that of altrenogest ).


2. In vivo research


According to its manufacturer Roussel Uclaf, altrenogest has weak anabolic and androgenic activity equivalent to 1 / 20th of that of testosterone. However, no significant androgenic effects have been observed in young stallions or mature mares, and altrenogest has notably been used to maintain pregnancy in mares ( similarly to the use of allylestrenol to maintain pregnancy in women ) with no incidence of virilization or other abnormalities in filly offspring. On the other hand, minor potential anabolic / androgenic effects have been suggested for altrenogest in pigs.





Product Catalogs


Fermentation ( Starting Materials & Intermediates ) Chemical Synthesis ( Intermediates )
4-androstenedione ( 4 - AD ) Dehydroepiandrosterone ( DHEA )
1,4-androstadienedione ( ADD ) Epiandrosterone
9a - hydroxy - 4 - androstenedione ( 9- OH -4- AD ) Androstanolone
21 - hydroxy - 20 - methylpregn - 4 - ene - 3 - one ( Bisnoralcohol, BA ) Mestanolone
Sitolactone ( δ- Lactone ) 17a-hydroxyprogesterone
11 a, 17 a - dihydroxyprogesterone 19-nor-4-androstenedione
11 a - hydroxy Canrenone Methyldienedione ( Estra -4,9- diene -3,17-dione )
3b,7a,15a - trihydroxyandrost - 5 - ene - 17- one Tertraene Acetate ( 3TR )
  Tertraene 21 - Methyl ( 5ST )
Chemical Synthesis ( API ) Canrenone
Spironolactone Estrone
Progesterone Chemical Synthesis ( API )
Estradiol & esters Testosterone & esters
Estriol Nandrolone & esters
Altrenogest Boldenone & esters
  Trenbolone & esters
  Metenolone & esters



Veterinary Powder Medicine Raw Materials Altrenogest Animal Pill CAS 850-52-2

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