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Star Anise Natural Plant Extracts 99% Shikimic Acid For Anti - Inflammatory / Analgesic

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Star Anise Natural Plant Extracts 99% Shikimic Acid For Anti - Inflammatory / Analgesic

China Star Anise Natural Plant Extracts 99% Shikimic Acid For Anti - Inflammatory / Analgesic supplier

Large Image :  Star Anise Natural Plant Extracts 99% Shikimic Acid For Anti - Inflammatory / Analgesic

Product Details:

Place of Origin: China
Brand Name: PooChun
Certification: HALAL KOSHER ISO HACCP GMP QS
Model Number: CAS 138-59-0

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1~10kg / Al-Pt bag, 10kg / 25kg fiber drum
Delivery Time: 1-3days after payment
Payment Terms: T/T, L/C
Supply Ability: 5000kg per Month
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Detailed Product Description
Variety: Star Anise Extract Test Method: HPLC
Specification: 99% Shikimic Acid HPLC Appearance: White Fine Powder
Trade Terms: FOB CNF CIF DAP DDU Payment Terms: T/T, Western Union, Paypal, Moneygram
Odor &Taste: Characteristic Shipping: DHL TNT FedEx EMS UPS By Sea By Air
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Star Anise Extract Natural Plant Extracts 99% Shikimic Acid for anti-inflammatory and analgesic

 

 

Description

 

Chinese herb Star Anise ( Illicium verum Hook. f. ) has been used in Chinese Medicine for centuries. Instead of normal use to flavor ingredients, it has also been widely used for the treatment of indigestion, stomach ache, colic in babies, and even facial paralysis. In recent years scientists have also found that star anise has possible cancer-fighting properties.

 

Shikimic acid is a white crystal compound of nonnitrogenous acid found in various plants naturally.Shikimic acid has two kind functional groups in the same molecule, three hydroxyl groups and a carboxylic acid group, which are optically active. They can yield various kinds of esters and salts.

 

The most important feature of cyclitol is that there are chiral isomers, key intermediates in the biosynthesis of aromatic compounds in living metabolism. Shikimic acid is a key intermediate in the biochemical pathway from phosphoenolpyruvic acid to tyrosine.

 

Shikimic acid is a precursor of many alkaloids, aromatic amino acids, and indole derivatives. Shikimic acid is widely used as a chiral building block for the synthesis of pharmaceuticals.

 

 

Use

 

In the pharmaceutical industry, shikimic acid from the Chinese star anise ( Illicium verum ) is used as a base material for production of oseltamivir ( Tamiflu ). Although shikimic acid is present in most autotrophic organisms, it is a biosynthetic intermediate and in general found in very low concentrations. The low isolation yield of shikimic acid from the Chinese star anise is blamed for the 2005 shortage of oseltamivir. Shikimic acid can also be extracted from the seeds of the sweetgum ( Liquidambar styraciflua ) fruit, which is abundant in North America, in yields of around 1.5%. For example, 4 kg of sweetgum seeds is needed for fourteen packages of Tamiflu. By comparison, star anise has been reported to yield 3 to 7% shikimic acid. Biosynthetic pathways in E. coli have recently been enhanced to allow the organism to accumulate enough material to be used commercially. A 2010 study released by the University of Maine showed that shikimic acid can also be readily harvested from the needles of several species of pine tree.

 

Protecting groups are more commonly used in small-scale laboratory work and initial development than in industrial production processes because their use adds additional steps and material costs to the process. However, the availability of a cheap chiral building block can overcome these additional costs e.g. shikimic acid for oseltamivir.

 

Aminoshikimic acid is also an alternative to shikimic acid as a starting material for the synthesis of oseltamivir.

 

 

99.0% Shikimic Acid HPLC Specification

 

Shikimic Acid 99% Shikimic Acid(HPLC)
Part Used Fruit Solvents Used Water&Ethanol
Botanical Source Illicium verum Hook .f Country of Origin China
ITEMS SPECIFICATION METHOD
Physical&Chemical Data
Color White Organoleptic
Odor & taste Characteristic Organoleptic
Appearance Fine Powder Organoleptic
Analytical Quality
Identification Identical to R.S.sample HPTLC
Curcumin ≥99.0% HPLC
Sieve analysis 100% through 80 mesh USP32<786>
Water(KF) ≤2.0% Eur.Ph.6.0<2.5.12>
Total Ash ≤1.0% Eur.Ph6.0<2.4.16>
Specific Rotation -185~-181 ° Eur.Ph.6.0 <2.9.13>
Contaminants
Lead (Pb) ≤3.0 mg/kg Eur.Ph.6.0<2.2.58>ICP-MS
Arsenic (As) ≤2.0 mg/kg Eur.Ph.6.0<2.2.58>ICP-MS
Mercury (Hg) ≤0.1 mg/kg Eur.Ph.6.0<2.2.58>ICP-MS
Cadmium (Cd) ≤1.0 mg/kg Eur.Ph.6.0<2.2.58>ICP-MS
Solvents Residue Meet Eur.Ph.6.0 <5.4> Eur.Ph.6.0<2.4.24>
Pesticides Residue Meet USP32<561> USP32<561>
Non irradiated ≤700 EN13751:2002<PSL>
Microbiology
  Irradiation Non irradiated  
Total Plate Count ≤1000cfu/g ≤10000cfu/g USP32<61>
Yeast&Mold ≤100cfu/g ≤1000cfu/g USP32<61>
E.coli. Negative Negative USP32<62>
Salmonella Negative Negative USP32<62>

 

 

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