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Pregnancy Hormones Pharmaceutical Raw Materials For Breasts Health / Endometrial Cancer

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Pregnancy Hormones Pharmaceutical Raw Materials For Breasts Health / Endometrial Cancer

China Pregnancy Hormones Pharmaceutical Raw Materials For Breasts Health / Endometrial Cancer supplier
Pregnancy Hormones Pharmaceutical Raw Materials For Breasts Health / Endometrial Cancer supplier Pregnancy Hormones Pharmaceutical Raw Materials For Breasts Health / Endometrial Cancer supplier

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Product Details:

Place of Origin: China
Brand Name: PooChun
Certification: ISO9001 SGS HACCP
Model Number: 57-83-0

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1~10 kg / Al-Pt bag,10kg / 25kg fiber drum
Delivery Time: 1-3days after payment
Payment Terms: T/T, L/C
Supply Ability: 500 ton per Month
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Detailed Product Description
Type: Estrogen Steroid Powder CAS: 57-83-0
Shipping: DHL TNT FedEx HKEMS UPS Use: Sexuality, Skin Health
Trade Terms: FOB CNF CIF DAP DDU Appearance: Powder
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pharmaceutical intermediates

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medicine raw material

Hormone of pregnancy Pharmaceutical Raw Materials for Breasts Health prevent endometrial cancer

 

 

Biosynthesis

 

Steroidogenesis, showing progesterone among the progestogens in yellow area.

 

In mammals, progesterone, like all other steroid hormones, is synthesized from pregnenolone, which itself is derived from cholesterol.

 

Cholesterol undergoes double oxidation to produce 22R - hydroxycholesterol and then 20α, 22R - dihydroxycholesterol. This vicinal diol is then further oxidized with loss of the side chain starting at position C22 to produce pregnenolone. This reaction is catalyzed by cytochrome P450scc.

 

The conversion of pregnenolone to progesterone takes place in two steps. First, the 3β - hydroxyl group is oxidized to a keto group and second, the double bond is moved to C4, from C5 through a keto/enol tautomerization reaction. This reaction is catalyzed by 3β - hydroxysteroid dehydrogenase/δ5-4 - isomerase.

 

Progesterone in turn is the precursor of the mineralocorticoid aldosterone, and after conversion to 17α - hydroxyprogesterone, of cortisol and androstenedione. Androstenedione can be converted to testosterone, estrone, and estradiol.

 

Pregnenolone and progesterone can also be synthesized by yeast.

 

The main physiological effects

  • Progesterone also has a role in skin elasticity and bone strength, in respiration, in nerve tissue and in female sexuality, and the presence of progesterone receptors in certain muscle and fat tissue may hint at a role in sexually dimorphic proportions of those.
  • During pregnancy, progesterone is said to decrease irritability.
  • During pregnancy, progesterone helps to suppress immune responses of the mother to fetal antigens, which prevents rejection of the fetus.
  • Progesterone raises epidermal growth factor-1 (EGF-1) levels, a factor often used to induce proliferation, and used to sustain cultures, of stem cells.
  • Progesterone increases core temperature (thermogenic function) during ovulation.
  • Progesterone reduces spasm and relaxes smooth muscle. Bronchi are widened and mucus regulated. (PRs are widely present in submucosal tissue.)
  • Progesterone acts as an antiinflammatory agent and regulates the immune response.
  • Progesterone reduces gall-bladder activity.
  • Progesterone normalizes blood clotting and vascular tone, zinc and copper levels, cell oxygen levels, and use of fat stores for energy.
  • Progesterone may affect gum health, increasing risk of gingivitis (gum inflammation).
  • Progesterone appears to prevent endometrial cancer (involving the uterine lining) by regulating the effects of estrogen.
  • Progesterone plays an important role in the signaling of insulin release and pancreatic function, and may affect the susceptibility to diabetes or gestational diabetes.
  • Progesterone may play a role in male behavior, such as in male aggression towards infants

 

 

Product Catalogs

 

Fermentation ( Starting Materials & Intermediates ) Chemical Synthesis ( Intermediates )
4-androstenedione ( 4 - AD ) Dehydroepiandrosterone ( DHEA )
1,4-androstadienedione ( ADD ) Epiandrosterone
9a - hydroxy - 4 - androstenedione ( 9- OH -4- AD ) Androstanolone
21 - hydroxy - 20 - methylpregn - 4 - ene - 3 - one ( Bisnoralcohol, BA ) Mestanolone
Sitolactone ( δ- Lactone ) 17a-hydroxyprogesterone
11 a, 17 a - dihydroxyprogesterone 19-nor-4-androstenedione
11 a - hydroxy Canrenone Methyldienedione ( Estra -4,9- diene -3,17-dione )
3b,7a,15a - trihydroxyandrost - 5 - ene - 17- one Tertraene Acetate ( 3TR )
  Tertraene 21 - Methyl ( 5ST )
Chemical Synthesis ( API ) Canrenone
Spironolactone Estrone
Stanozolol  
Progesterone Chemical Synthesis ( API )
Estradiol & esters Testosterone & esters
Estriol Nandrolone & esters
Altrenogest Boldenone & esters
  Trenbolone & esters
  Metenolone & esters

 

 

Pregnancy Hormones Pharmaceutical Raw Materials For Breasts Health / Endometrial Cancer

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