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PDE5 Inhibitor Medicine Raw Material Tadalafil Powder For Male Erectile Dysfunction 171596-29-5

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PDE5 Inhibitor Medicine Raw Material Tadalafil Powder For Male Erectile Dysfunction 171596-29-5

China PDE5 Inhibitor Medicine Raw Material Tadalafil Powder For Male Erectile Dysfunction 171596-29-5 supplier

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Product Details:

Place of Origin: China
Brand Name: PooChun
Certification: ISO9001 SGS HACCP
Model Number: 171596-29-5

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1~10 kg / Al-Pt bag,10kg / 25kg fiber drum
Delivery Time: 1-3days after payment
Payment Terms: T/T, L/C
Supply Ability: 100 ton per Month
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Detailed Product Description
CAS: 171596-29-5 Appearance: White Powder
MF: C22H19N3O4 Grade: Pharmaceutical Grade
Payment Terms: T/T, Western Union, Paypal, Moneygram Trade Terms: FOB CNF CIF DAP DDU
Shipping: DHL TNT FedEx HKEMS UPS Assay: 99.5% By HPLC
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PDE5 Inhibitor Medicine Raw Material Tadalafil For Male Erectile Dysfunction 171596-29-5

 

 

Description

 

Tadalafil ( INN ) is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction ( ED ) under the name Cialis / siˈælᵻs / see - AL - iss, and under the name Adcirca / ædˈsɜːrkə / ad - SUR - kə for the treatment of pulmonary arterial hypertension. In October 2011 the U.S. Food and Drug Administration ( FDA ) approved Cialis for treating the signs and symptoms of benign prostatic hyperplasia ( BPH ) as well as a combination of BPH and erectile dysfunction when the conditions coincide.

 

It initially was developed by the biotechnology company ICOS, and then again developed and marketed worldwide by Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. Cialis tablets, in 2.5 mg, 5 mg, 10 mg, and 20 mg doses, are yellow, film - coated, and almond - shaped. The approved dose for pulmonary arterial hypertension is 40 mg ( two 20 mg tablets ) once daily.

 

Product name

Tadalafil

Other name

cialis; chinacialis

CAS register number

171596-29-5

EINECS

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Molecular formula

C22H19N3O4

Molecular weight

389.341

Molecular structure

Cialis Male Enhancer Tadalafil Citrate Raw Sex Powder 171596-29-5

Assay

99%

Appearance

White powder

Package

1kg/aluminium foil bag or as required

Usage

can be used as pharmaceutical material

 

Drug interactions

 

Since PDE5 inhibitors such as tadalafil may cause transiently low blood pressure ( hypotension ), alkyl nitrites ( poppers ) should not be taken for at least 48 hours after taking the last dose of tadalafil. Using poppers ( such as the sex drug amyl nitrite ) within this timeframe may increase the risk of life - threatening hypotension.

 

Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina ( such as glyceryl trinitrate spray ), these patients should seek immediate medical attention if they experience anginal chest pain. In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.

 

Tadalafil is metabolized predominantly by the hepatic CYP3A4 enzyme system. The presence of other drugs which induce this system can shorten tadalafil half - life and reduce serum levels, and hence efficacy, of the drug.

 

 

Specification

 

Test Items Specification Test Results
Appearance White powder Conforms
Test method High pressure liquid chromatography(HPLC) Conforms
Melting Point 300℃~303℃ 301.5℃-302.6℃
Loss on drying ≤0.5% 0.24%
Heavy metals(Pb) ≤20ppm 7.5ppm
Residue on ignition ≤0.1% 0.08%
Relative substance ≤1.0% 0.145%
Assay (on dried basis) ≥98.5% 99.53%
Conclusion The product conform to USP 32

 

 

PDE5 Inhibitor Medicine Raw Material Tadalafil Powder For Male Erectile Dysfunction 171596-29-5

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