Payment & Shipping Terms:
|Trade Terms:||FOB CNF CIF DAP DDU||Shipping:||DHL TNT FedEx HKEMS UPS|
|Payment Terms:||T/T, Western Union, Paypal, Moneygram||Type:||4 - Nitrogen Heterosteroidal Compounds|
pharmaceutical raw materials
Steroid Hormones Medicine Raw Material Finasteride For Male Sex Hormones Propecia Hair Regrowth
Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used for the treatment of benign prostatic hyperplasia ( enlarged prostate ) and male pattern hair loss. It is a type II and type III 5α - reductase inhibitor; 5α - reductase, an enzyme, converts testosterone to dihydrotestosterone ( DHT ).
1. Prostate enlargement
Physicians sometimes use finasteride for the treatment of BPH, informally known as an enlarged prostate. Finasteride may improve the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow. It provides less symptomatic relief than alpha -1 blockers such as tamsulosin and symptomatic relief is slower in onset ( six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment ). Symptomatic benefits are mainly seen in those with prostate volume > 40 cm3. In long - term studies finasteride but not alpha-1 inhibitors reduce the risk of acute urinary retention ( −57% at 4 years ) and the need for surgery ( −54% at 4 years ). If the drug is discontinued, any therapeutic benefits reverse within about 6–8 months.
2. Pattern hair loss
Finasteride is sometimes used to treat pattern hair loss ( androgenetic alopecia ) in men only. Treatment slows further hair loss and provides about 30% improvement in hair loss after six months of treatment, with effectiveness usually only persisting as long as the drug is taken, although on occasion hair loss is slowed indefinitely following withdrawal. Finasteride has also been tested for pattern hair loss in women; the results were no better than placebo.
3. Excessive hair growth
Finasteride has been found to be effective in the treatment of hirsutism ( excessive facial and/or body hair growth ) in women. In a study of 89 women with hyperandrogenism due to persistent adrenarche syndrome, finasteride produced a 93% reduction in facial hirsutism and a 73% reduction bodily hirsutism after 2 years of treatment. Other studies using finasteride for hirsutism have also found it to be clearly effective.
4. Transgender women
Finasteride is sometimes used in hormone replacement therapy for transgender women due to its antiandrogen properties, in combination with a form of estrogen. However, little clinical research of finasteride use for this purpose has been conducted and evidence of efficacy is limited. Moreover, caution has been recommended when prescribing finasteride to transgender women, as finasteride may be associated with side effects such as depression, anxiety, and suicidal ideation, symptoms that are particularly prevalent in the transgender population and in others at high risk already.
|Test Items||Specification||Test Results|
|Description||White or off-white crystalline powder||Off-white crystalline powder|
|Identification||IR||Matches with working standard||Complies|
|Solubility||Freely soluble in chloroform and in alcohol;
Very slightly soluble in water
|Residue on ignition||≤0.1%||0.05%|
|Relative material||Maximum impurities≤0.5%||0.36%|
|Conclusion||The specification conform with Enterprise standard|