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Female Sex Hormones Pharmaceutical Raw Materials Progesterone CAS 57-83-0

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Female Sex Hormones Pharmaceutical Raw Materials Progesterone CAS 57-83-0

China Female Sex Hormones Pharmaceutical Raw Materials Progesterone CAS 57-83-0 supplier

Large Image :  Female Sex Hormones Pharmaceutical Raw Materials Progesterone CAS 57-83-0

Product Details:

Place of Origin: China
Brand Name: PooChun
Certification: ISO9001 SGS HACCP
Model Number: 57-83-0

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1~10 kg / Al-Pt bag,10kg / 25kg fiber drum
Delivery Time: 1-3days after payment
Payment Terms: T/T, L/C
Supply Ability: 500 ton per Month
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Detailed Product Description
CAS: 57-83-0 Test Method: HPLC
MF: C21H30O2 Appearance: White Powder
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pharmaceutical intermediates


medicine raw material

Female Sex Hormone Pharmaceutical Raw Materials Progesterone for Breast Cancer Treatment





Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid.


Hormonal interactions


Progesterone has a number of physiological effects that are amplified in the presence of estrogens. Estrogens through estrogen receptors ( ERs ) induce or upregulate the expression of the PR. One example of this is in breast tissue, where estrogens allow progesterone to mediate lobuloalveolar development.

Elevated levels of progesterone potently reduce the sodium - retaining activity of aldosterone, resulting in natriuresis and a reduction in extracellular fluid volume. Progesterone withdrawal, on the other hand, is associated with a temporary increase in sodium retention ( reduced natriuresis, with an increase in extracellular fluid volume ) due to the compensatory increase in aldosterone production, which combats the blockade of the mineralocorticoid receptor by the previously elevated level of progesterone.


Reproductive system

Micrograph showing changes to the endometrium due to progesterone ( decidualization ) H & E stain.

Progesterone has key effects via non-genomic signalling on human sperm as they migrate through the female tract before fertilization occurs, though the receptor ( s ) as yet remain unidentified. Detailed characterisation of the events occurring in sperm in response to progesterone has elucidated certain events including intracellular calcium transients and maintained changes, slow calcium oscillations, now thought to possibly regulate motility. It is produced by the ovaries. Interestingly, progesterone has also been shown to demonstrate effects on octopus spermatozoa.



Product Catalogs


Fermentation ( Starting Materials & Intermediates ) Chemical Synthesis ( Intermediates )
4-androstenedione ( 4 - AD ) Dehydroepiandrosterone ( DHEA )
1,4-androstadienedione ( ADD ) Epiandrosterone
9a - hydroxy - 4 - androstenedione ( 9- OH -4- AD ) Androstanolone
21 - hydroxy - 20 - methylpregn - 4 - ene - 3 - one ( Bisnoralcohol, BA ) Mestanolone
Sitolactone ( δ- Lactone ) 17a-hydroxyprogesterone
11 a, 17 a - dihydroxyprogesterone 19-nor-4-androstenedione
11 a - hydroxy Canrenone Methyldienedione ( Estra -4,9- diene -3,17-dione )
3b,7a,15a - trihydroxyandrost - 5 - ene - 17- one Tertraene Acetate ( 3TR )
  Tertraene 21 - Methyl ( 5ST )
Chemical Synthesis ( API ) Canrenone
Spironolactone Estrone
Progesterone Chemical Synthesis ( API )
Estradiol & esters Testosterone & esters
Estriol Nandrolone & esters
Altrenogest Boldenone & esters
  Trenbolone & esters
  Metenolone & esters



Female Sex Hormones Pharmaceutical Raw Materials Progesterone CAS 57-83-0

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